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Archive / FAA Pilot’s Handbook of Aeronautical Knowledge / Pilot’s Handbook: Chapter 17 — Aeromedical Factors

Chapter 17, Part 1

Aeromedical Factors — Part 1

FAA-H-8083-25C (2023)

Introduction

It is important for a pilot to be aware of the mental and

physical standards required for the type of flying performed.

This chapter provides information on medical certification and

on a variety of aeromedical factors related to flight activities.

Aeromedical

Factors

Chapter 17

Obtaining a Medical Certificate

Most pilots must have a valid medical certificate to exercise

the privileges of their airman certificates. Glider and free

balloon pilots are not required to hold a medical certificate.

Sport pilots may hold either a medical certificate or a valid

state driver’s license. Regardless of whether a medical

certificate or drivers license is required, 14 CFR 61.53

requires every pilot not to act as a crewmember if they know,

or have reason to know, of any medical condition that would

make them unable to operate the aircraft in a safe manner.

Acquisition of a medical certificate requires an examination

by an aviation medical examiner (AME), a physician

with training in aviation medicine designated by the Civil

Aerospace Medical Institute (CAMI). There are three classes

of medical certificates. The class of certificate needed

depends on the type of flying the pilot plans to perform.

A third-class medical certificate is required for a private or

recreational pilot certificate. It is valid for 5 years for those

individuals who have not reached the age of 40; otherwise it

is valid for 2 years. A commercial pilot certificate requires at

least a second-class medical certificate, which is valid for 1

year. First-class medical certificates are required for airline

transport pilots and are valid for one year if the airman is 40

or younger; 40 and older it is valid for 6 months.

The standards are more rigorous for the higher classes of

certificates. A pilot with a higher class medical certificate

has met the requirements for the lower classes as well. Since

the required medical class applies only when exercising the

privileges of the pilot certificate for which it is required, a

first-class medical certificate would be valid for 1 year if

exercising the privileges of a commercial certificate and 2 or 5

years, as appropriate, for exercising the privileges of a private

or recreational certificate. The same applies for a second-class

medical certificate. The standards for medical certification

are contained in Title 14 of the Code of Federal Regulations

(14 CFR) part 67 and the requirements for obtaining medical

certificates can be found in 14 CFR part 61.

Students who have physical limitations, such as impaired

vision, loss of a limb, or hearing impairment may be issued

a medical certificate valid for “student pilot privileges only”

while learning to fly. Pilots with disabilities may require

special equipment to be installed in the aircraft, such as

hand controls for pilots with paraplegia. Some disabilities

necessitate a limitation on the individual’s certificate; for

example, impaired hearing would require the limitation

“not valid for flight requiring the use of radio.” When all the

knowledge, experience, and proficiency requirements have

been met and a student can demonstrate the ability to operate

the aircraft with the normal level of safety, a “statement of

demonstrated ability” (SODA) can be issued. This waiver,

or SODA, is valid as long as the physical impairment does

not worsen. Contact the local Flight Standards District Office

(FSDO) for more information on this subject.

The FAA medical standards, 14 CFR part 67, specify fifteen

medical conditions that are considered disqualifying by

“history or clinical diagnosis.” Regardless of when one of

these conditions was diagnosed and treated, an airman may

not be issued a medical certificate except through a process

called a “Special Issuance Authorization,” as explained

in 14 CFR part 67, section 67.401. A special issuance is a

discretionary issuance by the FAA Federal Air Surgeon and

requires satisfactory completion of special testing determined

by the FAA to demonstrate that an airman is safe to fly for

the duration of the medical certificate issued. The specific

disqualifying conditions include:

• Diabetes mellitus requiring oral hypoglycemic

medication or insulin

• Angina pectoris

• Coronary heart disease that has been treated or, if

untreated, that has been symptomatic or clinically

significant

• Myocardial infarction

• Cardiac valve replacement

• Permanent cardiac pacemaker

• Heart replacement

• Psychosis

• Bipolar disorder

• Personality disorder that is severe enough to have

repeatedly manifested itself by overt acts

• Substance dependence (including alcohol)

• Substance abuse

• Epilepsy

• Disturbance of consciousness and without satisfactory

explanation of cause

• Transient loss of control of nervous system function(s)

without satisfactory explanation of cause

However, this list includes only the mandatory disqualifying

conditions. There are many other medical conditions that fall

into the General Medical Condition section of the regulations

that are considered by the FAA to be disqualifying even

though they are not stated in the regulations. Conditions

such as cancer, kidney stones, neurologic and neuromuscular

conditions including Parkinson’s disease and multiple

sclerosis, certain blood disorders, and other conditions that

may progress over time require review by the FAA before a

medical certificate may be issued.

The important thing to remember is that with very few

exceptions, all disqualifying medical conditions may

be considered for special issuance. If you can present

satisfactory medical documentation to the FAA that your

condition is stable, the chances are good that you will be

able to qualify for an Authorization.

Health and Physiological Factors

Affecting Pilot Performance

A number of health factors and physiological effects can be

linked to flying. Some are minor, while others are important

enough to require special attention to ensure safety of flight.

In some cases, physiological factors can lead to inflight

emergencies. Some important medical factors that a pilot

should be aware of include hypoxia, hyperventilation,

middle ear and sinus problems, spatial disorientation, motion

sickness, carbon monoxide (CO) poisoning, stress and

fatigue, dehydration, and heatstroke. Other subjects include

the effects of alcohol and drugs, anxiety, and excess nitrogen

in the blood after scuba diving.

Hypoxia

Hypoxia means “reduced oxygen” or “not enough oxygen.”

Although any tissue will die if deprived of oxygen long

enough, the greatest concern regarding hypoxia during

flight is lack of oxygen to the brain, since it is particularly

vulnerable to oxygen deprivation. Any reduction in mental

function while flying can result in life-threatening errors.

Hypoxia can be caused by several factors, including an

insufficient supply of oxygen, inadequate transportation of

oxygen, or the inability of the body tissues to use oxygen.

The forms of hypoxia are based on their causes:

• Hypoxic hypoxia

• Hypemic hypoxia

• Stagnant hypoxia

• Histotoxic hypoxia

Hypoxic Hypoxia

Hypoxic hypoxia is a result of insufficient oxygen available

to the body as a whole. A blocked airway and drowning

are obvious examples of how the lungs can be deprived of

oxygen, but the reduction in partial pressure of oxygen at high

altitude is an appropriate example for pilots. Although the

percentage of oxygen in the atmosphere is constant, its partial

pressure decreases proportionately as atmospheric pressure

decreases. As an aircraft ascends during flight, the percentage

of each gas in the atmosphere remains the same, but there are

fewer molecules available at the pressure required for them

to pass between the membranes in the respiratory system.

This decrease in number of oxygen molecules at sufficient

pressure can lead to hypoxic hypoxia.

Dangers of Transporting Dry Ice

Sublimation is a process in which a substance transitions

from a solid to a gaseous state without passing through

an intermediate liquid state. Dry ice sublimates into large

quantities of CO2 gas, which can rapidly displace oxygen-

containing air and potentially cause hypoxia via carbon

dioxide intoxication. Case studies have shown that both illness

and death can be caused by occupational and/or unintentional

exposure when transporting dry ice in small, confined

spaces such as a flightdeck or airplane. Exposure to high

concentration of CO2 gas may lead to increased respiration,

tachycardia, cardiac arrhythmia, and unconsciousness.

Exposure to concentration of CO2 gas in excess of 10 percent

may cause convulsions, coma, and/or death.

The tendency of dry ice to rapidly sublimate also means that

without proper ventilation, it can rapidly pressurize. For

this reason, dry ice should never be placed inside a sealed

transport container (i.e., leak-proof secondary container)

and must be placed within an outer shipping container or

storage container that allows adequate ventilation to release

the CO2 gas and avoid pressurization. Sealing dry ice within a

leak-proof container may result in explosion of the container

potentially leading to serious physical injury or death.

Hypemic Hypoxia

Hypemic hypoxia occurs when the blood is not able to take

up and transport a sufficient amount of oxygen to the cells

in the body. Hypemic means “not enough blood.” This type

of hypoxia is a result of oxygen deficiency in the blood,

rather than a lack of inhaled oxygen, and can be caused by

a variety of factors. It may be due to reduced blood volume

(from severe bleeding), or it may result from certain blood

diseases, such as anemia. More often, hypemic hypoxia

occurs because hemoglobin, the actual blood molecule that

transports oxygen, is chemically unable to bind oxygen

molecules. The most common form of hypemic hypoxia is

CO poisoning. This is explained in greater detail later in this

chapter. Hypemic hypoxia can also be caused by the loss

of blood due to blood donation. Blood volume can require

several weeks to return to normal following a donation.

Although the effects of the blood loss are slight at ground

level, there are risks when flying during this time.

Stagnant Hypoxia

Stagnant means “not flowing,” and stagnant hypoxia or

ischemia results when the oxygen-rich blood in the lungs

is not moving, for one reason or another, to the tissues that

Figure 17-1. Time of useful consciousness.

Altitude Time of useful consciousness

45,000 feet MSL

40,000 feet MSL

35,000 feet MSL

30,000 feet MSL

28,000 feet MSL

25,000 feet MSL

22,000 feet MSL

20,000 feet MSL

9 to 15 seconds

15 to 20 seconds

30 to 60 seconds

1 to 2 minutes

2½ to 3 minutes

3 to 5 minutes

5 to 10 minutes

30 minutes or more

need it. An arm or leg “going to sleep” because the blood

flow has accidentally been shut off is one form of stagnant

hypoxia. This kind of hypoxia can also result from shock,

the heart failing to pump blood effectively, or a constricted

artery. During flight, stagnant hypoxia can occur with

excessive acceleration of gravity (Gs). Cold temperatures

can also reduce circulation and decrease the blood supplied

to extremities.

Histotoxic Hypoxia

The inability of the cells to effectively use oxygen is defined

as histotoxic hypoxia. “Histo” refers to tissues or cells, and

“toxic” means poisonous. In this case, enough oxygen is being

transported to the cells that need it, but they are unable to make

use of it. This impairment of cellular respiration can be caused

by alcohol and other drugs, such as narcotics and poisons.

Research has shown that drinking one ounce of alcohol can

equate to an additional 2,000 feet of physiological altitude.

Symptoms of Hypoxia

High-altitude flying can place a pilot in danger of becoming

hypoxic. Oxygen starvation causes the brain and other vital

organs to become impaired. The first symptoms of hypoxia

can include euphoria and a carefree feeling. With increased

oxygen starvation, the extremities become less responsive and

flying becomes less coordinated. The symptoms of hypoxia

vary with the individual, but common symptoms include:

• Cyanosis (blue fingernails and lips)

• Headache

• Decreased response to stimuli and increased reaction

time

• Impaired judgment

• Euphoria

• Visual impairment

• Drowsiness

• Lightheaded or dizzy sensation

• Tingling in fingers and toes

• Numbness

As hypoxia worsens, the field of vision begins to narrow and

instrument interpretation can become difficult. Even with all

these symptoms, the effects of hypoxia can cause a pilot to

have a false sense of security and be deceived into believing

everything is normal.

Treatment of Hypoxia

Treatment for hypoxia includes flying at lower altitudes and/

or using supplemental oxygen. All pilots are susceptible

to the effects of oxygen starvation, regardless of physical

endurance or acclimatization. When flying at high altitudes,

it is paramount that oxygen be used to avoid the effects of

hypoxia. The term “time of useful consciousness” describes

the maximum time the pilot has to make rational, life-saving

decisions and carry them out at a given altitude without

supplemental oxygen. As altitude increases above 10,000

feet, the symptoms of hypoxia increase in severity, and the

time of useful consciousness rapidly decreases. [Figure 17-1]

Since symptoms of hypoxia can be different for each

individual, the ability to recognize hypoxia can be greatly

improved by experiencing and witnessing the effects of it

during an altitude chamber “flight.” The Federal Aviation

Administration (FAA) provides this opportunity through

aviation physiology training, which is conducted at the FAA

CAMI in Oklahoma City, Oklahoma, and at many military

facilities across the United States. For information about the

FAA’s one-day physiological training course with altitude

chamber and vertigo demonstrations, visit the FAA website

at www.faa.gov.

Hyperventilation

Hyperventilation is the excessive rate and depth of respiration

leading to abnormal loss of carbon dioxide from the blood.

This condition occurs more often among pilots than is

generally recognized. It seldom incapacitates completely, but

it causes disturbing symptoms that can alarm the uninformed

pilot. In such cases, increased breathing rate and anxiety

further aggravate the problem. Hyperventilation can lead to

unconsciousness due to the respiratory system’s overriding

mechanism to regain control of breathing.

Pilots encountering an unexpected stressful situation may

subconsciously increase their breathing rate. If flying at

higher altitudes, either with or without oxygen, a pilot may

have a tendency to breathe more rapidly than normal, which

often leads to hyperventilation.

Since many of the symptoms of hyperventilation are similar

to those of hypoxia, it is important to correctly diagnose and

treat the proper condition. If using supplemental oxygen,

check the equipment and flow rate to ensure the symptoms are

Figure 17-2. The Eustachian tube allows air pressure to equalize

in the middle ear.

Opening to throat

Middle ear

Outer ear

Auditory canal

Eustachian tube

Eardrum

not hypoxia related. Common symptoms of hyperventilation

include:

• Visual impairment

• Unconsciousness

• Lightheaded or dizzy sensation

• Tingling sensations

• Hot and cold sensations

• Muscle spasms

The treatment for hyperventilation involves restoring

the proper carbon dioxide level in the body. Breathing

normally is both the best prevention and the best cure

for hyperventilation. In addition to slowing the breathing

rate, breathing into a paper bag or talking aloud helps to

overcome hyperventilation. Recovery is usually rapid once

the breathing rate is returned to normal.

Middle Ear and Sinus Problems

During climbs and descents, the free gas formerly present in

various body cavities expands due to a difference between

the pressure of the air outside the body and that of the air

inside the body. If the escape of the expanded gas is impeded,

pressure builds up within the cavity and pain is experienced.

Trapped gas expansion accounts for ear pain and sinus pain,

as well as a temporary reduction in the ability to hear.

The middle ear is a small cavity located in the bone of the

skull. It is closed off from the external ear canal by the

eardrum. Normally, pressure differences between the middle

ear and the outside world are equalized by a tube leading

from inside each ear to the back of the throat on each side

called the Eustachian tube. These tubes are usually closed but

open during chewing, yawning, or swallowing to equalize

pressure. Even a slight difference between external pressure

and middle ear pressure can cause discomfort. [Figure 17-2]

During a climb, middle ear air pressure may exceed the

pressure of the air in the external ear canal causing the

eardrum to bulge outward. Pilots become aware of this

pressure change when they experience alternate sensations

of “fullness” and “clearing.” During descent, the reverse

happens. While the pressure of the air in the external ear

canal increases, the middle ear cavity, which equalized with

the lower pressure at altitude, is at lower pressure than the

external ear canal. This results in the higher outside pressure

causing the eardrum to bulge inward.

This condition can be more difficult to relieve due to the

fact that the partial vacuum tends to constrict the walls of

the Eustachian tube. To remedy this often painful condition,

which also causes a temporary reduction in hearing

sensitivity, pinch the nostrils shut, close the mouth and lips,

and blow slowly and gently into the mouth and nose.

This procedure forces air through the Eustachian tube into the

middle ear. It may not be possible to equalize the pressure in

the ears if a pilot has a cold, an ear infection, or sore throat.

A flight in this condition can be extremely painful, as well as

damaging to the eardrums. If experiencing minor congestion,

nose drops or nasal sprays may reduce the risk of a painful

ear blockage. Before using any medication, check with an

AME to ensure that it will not affect the ability to fly.

In a similar way, air pressure in the sinuses equalizes with

the pressure in the flight deck through small openings

that connect the sinuses to the nasal passages. An upper

respiratory infection, such as a cold or sinusitis, or a nasal

allergic condition can produce enough congestion around an

opening to slow equalization. As the difference in pressure

between the sinuses and the flight deck increases, congestion

may plug the opening. This “sinus block” occurs most

frequently during descent. Slow descent rates can reduce the

associated pain. A sinus block can occur in the frontal sinuses,

located above each eyebrow, or in the maxillary sinuses,

located in each upper cheek. It usually produces excruciating

pain over the sinus area. A maxillary sinus block can also

make the upper teeth ache. Bloody mucus may discharge

from the nasal passages.

Sinus block can be avoided by not flying with an upper

respiratory infection or nasal allergic condition. Adequate

protection is usually not provided by decongestant sprays

or drops to reduce congestion around the sinus openings.

Oral decongestants have side effects that can impair pilot

performance. If a sinus block does not clear shortly after

landing, a physician should be consulted.

Figure 17-3. The semicircular canals lie in three planes and sense motions of roll, pitch, and yaw.

YAW

ROLL

YAW

PITCH

PITCH ROLL

The semicircular tubes are arranged

at approximately, right angles to each

other in the roll, pitch, and yaw axes. Vestibular nerve

Endolymph fluid

Ampulla of semicircular canal

Hair cells

Cupola

Semicircular canals

Otolith organ

Spatial Disorientation and Illusions

Spatial disorientation specifically refers to the lack of

orientation with regard to the position, attitude, or movement

of the airplane in space. The body uses three integrated

systems that work together to ascertain orientation and

movement in space.

• Vestibular system—organs found in the inner ear that

sense position by the way we are balanced

• Somatosensory system—nerves in the skin, muscles,

and joints that, along with hearing, sense position

based on gravity, feeling, and sound

• Visual system—eyes, which sense position based on

what is seen

All this information comes together in the brain and, most

of the time, the three streams of information agree, giving

a clear idea of where and how the body is moving. Flying

can sometimes cause these systems to supply conflicting

information to the brain, which can lead to disorientation.

During flight in visual meteorological conditions (VMC),

the eyes are the major orientation source and usually prevail

over false sensations from other sensory systems. When

these visual cues are removed, as they are in instrument

meteorological conditions (IMC), false sensations can cause

a pilot to quickly become disoriented.

The vestibular system in the inner ear allows the pilot to

sense movement and determine orientation in the surrounding

environment. In both the left and right inner ear, three

semicircular canals are positioned at approximate right angles

to each other. [Figure 17-3] Each canal is filled with fluid

and has a section full of fine hairs. Acceleration of the inner

ear in any direction causes the tiny hairs to deflect, which

in turn stimulates nerve impulses, sending messages to the

brain. The vestibular nerve transmits the impulses from

the utricle, saccule, and semicircular canals to the brain to

interpret motion.

The somatosensory system sends signals from the skin, joints,

and muscles to the brain that are interpreted in relation to the

Earth’s gravitational pull. These signals determine posture.

Inputs from each movement update the body’s position to the

brain on a constant basis. “Seat of the pants” flying is largely

dependent upon these signals. Used in conjunction with visual

and vestibular clues, these sensations can be fairly reliable.

However, the body cannot distinguish between acceleration

forces due to gravity and those resulting from maneuvering

the aircraft, which can lead to sensory illusions and false

impressions of an aircraft’s orientation and movement.

Under normal flight conditions, when there is a visual

reference to the horizon and ground, the sensory system in the

inner ear helps to identify the pitch, roll, and yaw movements

of the aircraft. When visual contact with the horizon is lost,

the vestibular system becomes unreliable. Without visual

references outside the aircraft, there are many situations in

which combinations of normal motions and forces create

convincing illusions that are difficult to overcome.

Prevention is usually the best remedy for spatial disorientation.

Unless a pilot has many hours of training in instrument flight,

flight should be avoided in reduced visibility or at night when

the horizon is not visible. A pilot can reduce susceptibility

to disorienting illusions through training and awareness and

learning to rely totally on flight instruments.

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